GPCR Signalling Complexes Synthesis, Assembly, Trafficking and Specificity by Ra

Description: GPCR Signalling Complexes Synthesis, Assembly, Trafficking and Specificity by Ralf Jockers, Denis J. Dupré, Terence E. Hébert Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways. How do GPCR signalling complexes get assembled to generate such specificity? Then, we need to understand how each partner of the signalling complex is selected to join a complex, and what makes this assembly possible. Publisher Description Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways. How do GPCR signalling complexes get assembled to generate such specificity? In order to answer this question, we need to understand how receptors and their signalling partners are synthesized, folded and quality-controlled in order to generate functional proteins. Then, we need to understand how each partner of the signalling complex is selected to join a complex, and what makes this assembly possible. GPCRs are known to be able to function as oligomers, what drives the assembly into oligomers and what will be the effects of such organization on specificity and efficacy of signal transduction. Once the receptor complexes are assembled, they need to reach different locations in the cell; what drives and controls the trafficking of GPCR signalling complexes. Finally, defects in synthesis, maturation or trafficking can alter functionality of GPCRs signalling complexes; how can we manipulate the system to make it function normally again? Pharmacological chaperones may just be part of the answer to this question. Details ISBN 9400747640 ISBN-13 9789400747647 Title GPCR Signalling Complexes Synthesis, Assembly, Trafficking and Specificity Author Ralf Jockers, Denis J. Dupré, Terence E. Hébert Format Hardcover Year 2012 Pages 300 Edition 2012th Publisher Springer GE_Item_ID:140325947; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

Price: 189.32 USD

Location: Fairfield, Ohio

End Time: 2025-01-26T03:38:03.000Z

Shipping Cost: 0 USD

Product Images

Item Specifics

Restocking Fee: No

Return shipping will be paid by: Buyer

All returns accepted: Returns Accepted

Item must be returned within: 30 Days

Refund will be given as: Money Back

ISBN-13: 9789400747647

Book Title: GPCR Signalling Complexes Synthesis, Assembly, Trafficking and S

Number of Pages: VIII, 300 Pages

Publication Name: Gpcr Signalling Complexes-Synthesis, Assembly, Trafficking and Specificity

Language: English

Publisher: Springer Netherlands

Publication Year: 2012

Subject: Pharmacology, Research, Chemistry / Organic

Type: Textbook

Item Weight: 22.4 Oz

Item Length: 9.3 in

Subject Area: Science, Medical

Author: Terence E. Hébert

Series: Subcellular Biochemistry Ser.

Item Width: 6.1 in

Format: Hardcover