Biomedical Nanostructures by Kenneth Gonsalves (English) Hardcover Book

Description: Biomedical Nanostructures by Kenneth Gonsalves, Craig Halberstadt, Cato T. Laurencin, Lakshmi Nair Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The texts three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications. Back Cover Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The texts three sections highlight its interdisciplinary approach: Part One: Nanostructure Fabrication Part Two: Bio-Nano Interfaces Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications. Flap Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The texts three sections highlight its interdisciplinary approach: Part One: Nanostructure Fabrication Part Two: Bio-Nano Interfaces Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications. Author Biography Kenneth E. Gonsalves, PhD, is Distinguished Professor in the Department of Chemistry at the University of North Carolina at Charlotte. Dr. Gonsalves has more than fifteen years of experience in using photolithography and chemistry to develop materials that have features at both the micron and nanoscale. Working with Dr. Craig Halberstadt, he has successfully demonstrated the ability to create a new material that can be controlled at both these size scales to influence cell behavior. He has also developed active polymeric nanoparticles for delivery of antibiotics and genes. Craig R. Halberstadt, PhD, is Director of Tissue Engineering and Senior Research Scientist at the Cannon Research Center of Carolinas Medical Center. Dr. Halberstadt is a pioneer in the development of a scalable commercial process for the growth of a human skin product. He has also published extensively on cell/biomaterial interactions for cellular transplantation. Cato T. Laurencin, MD, PhD, is Lillian T. Pratt Distinguished Professor and Chair of the Department of Orthopaedic Surgery and Professor of Biomedical Engineering and Chemical Engineering at the University of Virginia. He has also been designated one of fifteen University Professors at the School. He has authored more than 250 peer-reviewed articles and has edited books in the areas of biomaterials, orthopaedic tissue engineering, and nanotechnology. He is the recipient of several national and international awards and was elected to the National Academy of Sciences, Institutes of Medicine. His current research interests include biomaterial synthesis, orthopaedic tissue engineering, gene therapy, drug delivery, and nanotechnology. Lakshmi S. Nair, MPhil, PhD, is Assistant Professor in the Department of Orthopaedic Surgery at the University of Virginia. She has authored more than fifty peer-reviewed articles in the areas of biomaterials, tissue engineering, drug delivery, and nanotechnology. Her research interests include hydrogels for tissue engineering and drug delivery, stimuli sensitive materials, and biomedical nanotechnology. Table of Contents PART I. NANOSTRUCTURE FABRICATION. 1. Nanofabrication Techniques. 2. Micro/ Nano-Machining and Fabrication of Materials for Biomedical Applications. 3. Novel Nanostructures as Molecular Nanomotors. 4. Bioconjugation of Soft Nanomaterials. 5. Nanotechnology and Drug Delivery. 6. Polymeric NanoParticles and Nanopore Membranes for Controlled Drug and Gene Delivery . 7. Development of Nanostructures for Drug Delivery Applications. 8. Bioconjugated Nanoparticles for Ultrasensitive Detection of Molecular Biomarkers and Infectious Agents. PART II. BIO-NANO INTERFACES. 9. ECM Interactions With Cells From The Meso To NanoScale. 10. Cell Behavior Towards Nanostructured Surfaces. 11. Cellular Behavior on Basement Membranes Inspired Topographically Patterned Synthetic Matrices. 12. Focal Adhesions: Self-Assembling Nanoscale Mechanochemical Machines that Control Cell Function. 13. Controlling Cell Behavior via DNA and RNA Transfections. 14. Multi-Scale Co-Culture Models for Orthopaedic Interface Tissue Engineering. PART III. CLINICAL APPLICATIONS OF NANOSTRUCTURES. 15. Nanostructures for Tissue Engineering/Regenerative Medicine. 16. Nanostructures for Cancer Therapy. 17. Clinical Applications of Micro-and NanoScale Biosensors. 18. Nanoscale Iron Compounds Related to Neurodegenerative Disorders. 19. Application of Nanotechnology into Life Science: Benefit or Risk. Review "...the book is a fruitful source of information and it is enjoyable to read thanks to nice illustrations. It will be of interest not only to students or scientists not familiar with these fields, but also to specialists, because of the large number of references, many as recent as 2006." (Macromol. Chem. Phys. 04/2008) Long Description Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The texts three sections highlight its interdisciplinary approach: Part One: Nanostructure Fabrication Part Two: Bio-Nano Interfaces Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications. Review Text "...the book is a fruitful source of information and it is enjoyable to read thanks to nice illustrations. It will be of interest not only to students or scientists not familiar with these fields, but also to specialists, because of the large number of references, many as recent as 2006." (Macromol. Chem. Phys. 04/2008) Review Quote "...the book is a fruitful source of information and it is enjoyable to read thanks to nice illustrations. It will be of interest not only to students or scientists not familiar with these fields, but also to specialists, because of the large number of references, many as recent as 2006." ( Macromol. Chem. Phys . 04/2008) Promotional "Headline" "...the book is a fruitful source of information and it is enjoyable to read thanks to nice illustrations. It will be of interest not only to students or scientists not familiar with these fields, but also to specialists, because of the large number of references, many as recent as 2006." (Macromol. Chem. Phys. 04/2008) Feature A comprehensive resource for one of the most exciting and most promising fields in biology and medicine, this book helps the reader to better understand the different physical phenomena that occur at the nano (and sometimes micron) scale, information that can accelerate the design of novel cell-based constructs for a wide range of applications. The book is divided into three sections: "Cell Biology at the Nano Scale"; "Material Processing"; and "Clinical Applications". Topics include: nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, cancer therapy, etc.; and nano- and microengineering and fabrication. The reference presents examples of the chemistry and processing involved in designing and developing nano/micron-scale materials for use in diagnostics, drug delivery, cancer therapy, and more. Clinical applications discussed include nano-based tissue engineering, drug delivery systems, biosensors, and motors. Thorough and in-depth, this reference explores the integration across interfaces and size scales from nano to micro, an area that is often overlooked and/or misunderstood. Details ISBN0471925527 Short Title BIOMEDICAL NANOSTRUCTURES Language English ISBN-10 0471925527 ISBN-13 9780471925521 Media Book Format Hardcover DEWEY 610.28 Illustrations Yes Year 2007 Alternative 9780470185834 Edited by Kenneth Gonsalves Edition 1st DOI 10.1604/9780471925521 UK Release Date 2007-12-11 AU Release Date 2007-12-11 NZ Release Date 2007-12-11 US Release Date 2007-12-11 Place of Publication Chicester Author Lakshmi Nair Publisher John Wiley & Sons Inc Publication Date 2007-12-11 Imprint Wiley-Interscience Country of Publication United States Audience Professional & Vocational Pages 544 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:137318370;

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